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Gene : |
RSAD2 |
Gene ID : |
91543 |
Uniprot ID : |
Q8WXG1 |
Alternative Name : |
RSAD2, CIG5 |
Format : |
Purified |
Amount : |
100 µg |
Isotype : |
Rabbit IgG |
Immunogen Information : |
A partial length recombinant Viperin protein (amino acids 100-330) was used as the immunogen for this antibody. |
Radical S-adenosyl methionine domain-containing protein 2 is commonly known as Viperin consisting of 43 kDa protein. which is a interferon inducible viral protein. Viperin expression is induced by IFN?, IFNb, IFNg, human cytomegalovirus (HCMV) envelope protein, glycoprotein B (gB), etc. Viperin interaction with the viral protein vMIA results in viperin relocalization from the endoplasmic reticulum to the mitochondria. It interacts with the mitochondrial trifunctional protein which mediates beta-oxidation of fatty acids to generate ATP. Viperin promotes TLR7 and TLR9-dependent production of IFN-beta and also plays an important role in CD4+ T-cell activation and differentiation. Viperin is highly expressed in mouse and human brain.
Western blot analysis: 3-5 µg/ml