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Alternative Name : |
AGP7, P29, PR-3, ACPA, C-ANCA, MBT, MBN, Leukocyte proteinase 3, Neutrophil proteinase 4, Wegener granulomatosis autoantigen, Azurophil granule protein 7, myeloblastin, Serine proteinase neutrophil. |
Amount : |
10 µg |
Source : Native.
PRTN3 is a natural antigen having a molecular mass of 25kDa to 32kDa due to glycosylation isoforms. PRTN3 is isolated from human peripheral blood leukocytes.
PRTN3 is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema once managed by tracheal insufflation to hamsters.