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Alternative Name : |
HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, ptp-IV1b, PTP4A, PTPCAAX2. |
Amount : |
10 µg |
Source : Escherichia Coli.
Recombinant Human PTP4A2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (1-167 a.a.) and having a molecular mass of 23.2 kDa. PTP4A2 is fused to a 36 amino acid His-Tag at N-Terminus and purified by conventional chromatography techniques.
PTP4A2 is part of a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that take part in a variety of cellular activities. PTP4A2 protein interacts with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), therefore has a role as a regulator of GGT II activity. Overexpression of PTP4A2 in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis.