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| Alternative Name : |
B70, B7-2, LAB72, CD28LG2, FUN-1, BU63. |
| Format : |
Purified |
| Amount : |
1 mg |
| Clone name : |
mB7-2. |
| Isotype : |
Rat IgG2a. |
| Immunogen Information : |
Purified mouse LPS-activated B cells. |
CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.
