Source : Baculovirus Recombinant Vietnam HN31242/2007 produced in Hi-5 cell of Baculovirus is a single polypeptide chain containing 332 amino acids (17-338) and having a molecular mass of 37.4kDa.H5N1 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. Influenza A virus subtype H5N1 is a subtype of the Influenza A virus. Subtype H5N1 is commonly known as avian influenza or bird flu. H5N1 may cause more than one influenza pandemicas it is expected to continue mutating in birds. The dominant strain of HPAI A (H5N1) evolved creating the Z genotype. It has also been called Asian lineage HPAI/A/H5N1 which is divided into 2 antigenic clades. 'Clade 1 includes human and bird isolates from Vietnam, Thailand, and Cambodia and bird isolates from Laos and Malaysia. Clade 2 viruses were first identified in bird isolates from China, Indonesia, Japan, and South Korea before spreading westward to the Middle East, Europe, and Africa.
