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Alternative Name : |
Beta-synuclein, SNCB, b-Synuclein. |
Amount : |
50 µg |
Source : Escherichia Coli.
Recombinant Human b-Synuclein produced in E.Coli is a single, non-glycosylated polypeptide chain (1-134 a.a) having a molecular mass of 14.2kDa (molecular size on SDS-PAGE will appear higher). SNCB is extremely heatresistant and has a chaperone-like activity. Recently, ?-synuclein has been suggested to inhibit ?-synuclein aggregation.
b-synuclein (amino acids 1-134), an acidic neuronal protein of 134 amino acids, is extremely heat-resistant. b-synucelin also has a chaperone-like activity. Recently, b-synuclein has been suggested to inhibit a-synuclein aggregation. b and a-synuclein are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease.