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| Alternative Name : |
Potassium Channel Subfamily M Regulatory Beta Subunit 3, Potassium
Large Conductance Calcium-Activated Channel, Subfamily M Beta Member 3, Calcium-Activated
Potassium Channel, Subfamily M Subunit Beta-3, Charybdotoxin Receptor Subunit
Beta-3, Big Pot |
| Amount : |
20 µg |
Source : Escherichia Coli.
KCNMB3 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 149 amino acids (82-207 a.a) and
having a molecular mass of 16.8kDa.
KCNMB3 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
The KCNMB3 belongs to a family of 4 auxiliary beta subunits found in the mammalian genome, which associate with Slo1 alpha subunits and regulate BK channel function. In humans, the KCNMB3 gene is comprised of 4 N-terminal alternative exons which produce 4 functionally distinct beta3 subunits, beta3a-d. Three variants, beta3a-c, display kinetically distinct inactivation behaviors.
