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| Alternative Name : |
CD47
Molecule, Antigenic Surface Determinant Protein OA3, CD47 Antigen (Rh-Related
Antigen, Integrin-Associated Signal Transducer), Antigen Identified by
Monoclonal, Antibody 1D8, Integrin Associated Protein, Integrin-Associated
Protein, Rh-Related, |
| Amount : |
10 µg |
Source : Sf9, Insect cells. CD47 Human Recombinant produced in Sf9 Insect cell is a single, non-glycosylated polypeptide chain containing 362 amino acids (19-141aa.a) and having a molecular mass of 40.9kDa (Migrates at 40-57kDa on SDS-PAGE under reducing conditions).CD47 is fused to a 239 amino acid hIgG-His-tag at C-terminus & purified by proprietary chromatographic techniques. CD47, functions in cell adhesions by performing as an adhesion receptor for THBS1 on platelets, furthermore CD47 plays a role in the modulation of integrins. In addition, CD47 takes a vital part in memory formation as well as synaptic plasticity in the hippocampus. Receptor for SIRPA avoids maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 prevents premature elimination of red blood cells, and it is also implicated in membrane permeability changes induced following virus infection.
