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| Alternative Name : |
Matrix Gla protein, Cell growth-inhibiting gene 36 protein, MGLAP, NTI. |
| Amount : |
20 µg |
Source : E.coli.
MGP Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 98 amino acids (20-96) and having a molecular mass of 11.8 kDa.The MGP is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
MGP is vital for the regulation of calcification in the extracellular matrix, particularly in cartilage and arteries. The K-dependent vitamin MGP has five to six residues of Gla, a Ca2+ binding amino acid crucial for vitamin K-dependent gamma carboxylase for its formation. MGP is formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity and localized in the human bone.
