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| Alternative Name : |
Microfibrillar-associated protein 2, MFAP-2, Microfibril-associated glycoprotein 1, MAGP, MAGP-1, MFAP2, MAGP1. |
| Amount : |
10 µg |
Source : Escherichia Coli.
MFAP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids (18-183 a.a) and having a molecular mass of 21.5kDa.MFAP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Microfibrillar-associated protein 2 (MFAP2) is an O-glycosylated protein discharged to the extracellular space and the extracellular matrix. MFAP2 connects with biglycan and elastin in a ternary complex. MFAP2 plays a key role in the support and distensibility of the juxtacanalicular region of these collector channels. MFAP2 inhibits LTB-1 binding to fibrillin-1, promotes the phosphorylation of Smad2 thus mediating the consequent extracellular deposition of latent TGFbeta.
