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Alternative Name : |
Modulator
Of Apoptosis 1, MAP1, PNMA4, Paraneoplastic Ma Antigen Family Member 4, Paraneoplastic
Antigen Ma4, MAP-1, Paraneoplastic Antigen Like 4. |
Amount : |
20 µg |
Source : Escherichia Coli.
MOAP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 374 amino acids (1-351a.a) and having a molecular mass of 41.9kDa.MOAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Modulator
of apoptosis 1 (MOAP1), is a member of the PNMA family and contains one BH3-like domain
and one RASSF1-binding domain. MOAP1 was recognized by its interaction with
apoptosis regulator BAX protein. MOAP1 includes a Bcl-2 homology 3 (BH3)-like
motif, which is essential for the association with BAX. In addition, once over
expressed MOAP1 mediates caspase-dependent apoptosis.