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| Alternative Name : |
p53 Mutant, p53 Mutant (a.a 135), Cellular tumor antigen p53, Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13, TP53, P53, LFS1, TRP53, FLJ92943. |
| Amount : |
5 µg |
Source : Escherichia Coli.
p53 Mutant Human Recombinant full length protein (a.a 135) expressed in E.coli, shows a 81 kDa band on SDS-PAGE.The p53 Mutant is purified by proprietary chromatographic techniques.
p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
