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| Alternative Name : |
AGOTC, PHOX1, PMX1, PRX-1, PRX1, Paired mesoderm homeobox
protein 1, Homeobox protein PHOX1, Paired-related homeobox protein 1, PRRX1. |
| Amount : |
10 µg |
Source : Escherichia Coli.
PRRX1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 241 amino acids (1-217 a.a) and having a molecular mass of 26.9kDa.PRRX1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
PRRX1
is part of the paired family of homeobox proteins. PRRX1 functions as a
transcription co-activator, enhancing the DNA-binding activity of serum response
factor, a protein required for the induction of genes by growth and
differentiation factors. PRRX1 also regulates muscle creatine kinase, and
therefore has a part in the establishment of diverse mesodermal muscle types. The
protein binds to an A/T-rich element in the muscle creatine enhancer. Among the
diseases associated with PRRX1 are agnathia-otocephaly complex, and pleomorphic
liposarcoma.
