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| Alternative Name : |
Profilin-II, PFN2, Profilin-2, PFL, D3S1319E. |
| Amount : |
10 µg |
Source : Escherichia Coli.
PFN2 Human Recombinant produced in E.Coli is a single, non-glycosylated,
polypeptide chain containing 160 amino acids (1-140 a.a.) and having a molecular mass of 17.2 kDa. PFN2 protein is fused to a 20 amino acid His-Tag at N-terminus and purified by standard chromatography.
PFN2 is a ubiquitous actin monomer-binding protein which is part of the profilin family. PFN2 regulates actin polymerization in response to extra cellular signals. PFN2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, while it increases it at low concentrations. PFN2 binds to PIP2, it inhibits the formation of IP3 and DG.
