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| Alternative Name : |
Hqk, hqkI, QK, QK1, QK3, Protein quaking, Quaking
Homolog, KH Domain RNA Binding, RNA Binding Protein HQK, HKQ, KH
Domain Containing, RNA Binding. |
| Amount : |
10 µg |
Source : Escherichia Coli.
QKI Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 364 amino acids (1-341 a.a) and having a molecular mass of 40.1kDa.QKI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
KH Domain RNA Binding also known as QKI is a
RNA-binding protein which regulates pre-mRNA splicing, export of mRNAs from the
nucleus, protein translation, and mRNA stability. QKI
is involved in myelinization
and oligodendrocyte differentiation, and it may play a role in schizophrenia.
Defects or deletions in the QKI
are linked with astrocytic tumors and may be implicated in the pathogenesis of
schizophrenia. Among the diseases associated with QKI are
6q terminal deletion syndrome, and schizophrenia.
