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| Alternative Name : |
Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Re |
| Amount : |
20 µg |
Source : E.coli.
RBBP4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 449 amino acids (1-425 a.a) and having a molecular mass of 50.2kDa.RBBP4 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Retinoblastoma binding protein 4 (RBBP4) is a ubiquitously expressed nuclear protein which is a member of a highly conserved subfamily of WD-repeat proteins. RBBP4 is present in protein complexes involved in histone acetylation and chromatin assembly. In addition, RBBP4 is part of co-repressor complexes, which is a fundamental component of transcriptional silencing. RBBP4 is observed among several cellular proteins which bind directly to a retinoblastoma protein to regulate cell proliferation. RBBP4 also is a part of the Mi-2 complex which is implicated in chromatin remodeling and transcriptional repression connected with histone deacetylation.
