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| Alternative Name : |
Retinoic acid early transcript 1G protein, RAET1G, ULBP5. |
| Amount : |
10 µg |
Source : Escherichia Coli.
RAET1G Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (corresponding to Isoform 2, Uniprot accession #Q6H3X3-2) containing 198 amino acids including a 10 a.a N-terminal His tag. The total molecular mass is 22.43kDa (calculated).
Retinoic Acid Early Transcript 1G (RAET1G/ULBP5) is a member of the MHC class I family. RAET1G functions as a ligand for the NKG2D receptor on the surface of NK cells. NKG2D stimulation influences anti-tumor and anti-viral immune responses of NK cells. ULBP ligands are generated by virally infected cells and tumors. RAET1G is expressed in 2 variants- a membrane and a soluble isoform. RAET1G is highly expressed in the colon and in several tumor cell lines.
It is recommended to add 200µl deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. RAET1G is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
