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| Alternative Name : |
Cornifin-B, 14.9 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B, SPRR1, GADD33, CORNIFIN. |
| Amount : |
10 µg |
Source : Escherichia Coli.
SPRR1B Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a 2-89) containing 97 amino acids including a 9 a.a N-terminal His tag. The total molecular mass is 10.9kDa (calculated).
Small Proline-Rich Protein 1B (SPRR1B) is a keratinocyte protein which first appears in the cell cytosol, but eventually becomes cross-linked to membrane proteins by transglutaminase. SPRR1B is cross-linked to membrane proteins by transglutaminase leading to formation of an insoluble envelope. SPRR1B functions as both amine donor and acceptor in transglutaminase-mediated cross-linkage. SPRR1B is expressed in the course of differentiation in squamous tissues such as epidermis, esophagus, tongue or trachea.
It is recommended to add 200µl deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. SPRR1B is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
