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|
| Alternative Name : |
TCBP, TIAR, TIA1 cytotoxic granule-associated RNA binding
protein-like 1, TIA-1-related protein. |
| Amount : |
20 µg |
Source : Escherichia Coli.
TIAL1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 398 amino acids (1-375 a.a) and
having a molecular mass of 44.0kDa.TIAL1 is fused
to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
TIAL1 belongs to a family of RNA-binding proteins, it has 3 RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a extensive range of genes. TIAL1 regulates a variety of activities including translational control, splicing and apoptosis. TIAL1 different isoforms function differently with respect to post-transcriptional silencing.
