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Alternative Name : |
TRAP-1, TRAP1, Transforming growth factor-beta receptor-associated
protein 1, TGF-beta receptor-associated protein 1. |
Amount : |
10 µg |
Source : Escherichia Coli.
TGFBRAP1 Human Recombinant produced in E.Coli is a
single, non-glycosylated polypeptide chain containing 296 amino acids (601-860 a.a)
and having a molecular mass of 33kDa.TGFBRAP1 is fused to a 36 amino acid His-tag at
N-terminus & purified by proprietary chromatographic techniques.
TGF-beta receptor-associated protein 1 also known
as TGFBRAP1 takes part in the TGF-beta/activin signaling pathway. TGFBRAP1 is
related with inactive heteromeric
TGF-beta and activin receptor complexes, mainly
through the type
II receptor, and is released
upon activation of signaling. TGFBRAP1recruits SMAD4 to the vicinity of the
receptor complex and smoothes the progress of its interaction with
receptor-regulated Smads, such as SMAD2.