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| Alternative Name : |
Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor
35 kDa subunit, U2 small nuclear RNA auxiliary factor 1, U2 snRNP auxiliary
factor small subunit, U2AF35, U2AFBP, FP793, RNU2AF1, RN. |
| Amount : |
20 µg |
Source : Escherichia Coli.
U2AF1 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 263 amino acids (1-240 a.a) and having
a molecular mass of 30.3kDa.U2AF1 is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
U2AF1
is a member of the splicing factor SR family. U2 auxiliary factor, comprising a
large and a small
subunit, is a non-snRNP protein essential for the binding of U2 snRNP to the
pre-mRNA branch site.U2AF1 is the small subunit which plays a vital role in
both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between
the large subunit and proteins bound to the enhancers. U2 small nuclear RNA
auxiliary factor 1 (U2AF1) is a protein-coding gene. Among the diseases which
are associated with U2AF1:Myoclonus Epilepsy and progressive Myoclonus Epilepsy.
