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Alternative Name : |
EC 1.17.4.1, RR2M, RR2, Ribonucleotide Reductase M2, R2, RRM2. |
Amount : |
25 µg |
Source : Escherichia Coli.
RRM2 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (1-389 a.a.) and having a molecular mass of 47 kDa. The RRM2 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
RRM2 catalyzes the formation of deoxyribonucleotides from ribonucleotides.
Synthesis RRM2 is regulated in a cell-cycle dependent method. RRM2 supplies the precursors essential for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 Inhibits Wnt signaling.