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Alternative Name : |
gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4, CD4mut. |
Amount : |
10 µg |
Source : Baculovirus.
sCD4 Human Recombinant produced in Baculovirus is a single, glycosylated polypeptide chain containing 365 amino acids and having a non glycosilated molecular mass of 45 kDa. As a result of glycosilation the sCD4 migrates as a 46 kDa protein on standard SDS-PAGE. Detected By Western Imunno Blots anti CD4 monoclonal antibody.The sCD4 is purified by proprietary chromatographic techniques.
CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.