|
|
Gene : |
BSG |
Gene ID : |
682 |
Uniprot ID : |
P35613 |
Alternative Name : |
BSG, UNQ6505/PRO21383 |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
BSG/963 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Recombinant human BSG protein |
This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);