|
|
| Gene : |
NR2F6 |
| Gene ID : |
2063 |
| Uniprot ID : |
P10588 |
| Alternative Name : |
NR2F6, EAR2, ERBAL2 |
| Format : |
Purified |
| Amount : |
100 µg |
| Isotype : |
Rabbit IgG |
| Immunogen Information : |
A partial length recombinant NR2F6 protein (amino acids 210-400) was used as the immunogen for this antibody. |
NR2F6 (Nuclear receptor subfamily 2 group F member 6) is a nuclear zinc-finger orphan receptor which acts as a critical PKC (protein kinase C) substrate and essential regulator of CD4(+) T cell activation responses. It Inhibits NFATC (Nuclear factor of activated T-cells) transcription factor DNA binding and subsequently its transcriptional activity. It acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. It is involved in development of forebrain circadian clock.
Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5 µg/ml
