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Alternative Name : |
Regulatory Subunit 22, MINOS3, PPP1R22, Mitochondrial
Inner Membrane Organizing System 3, Protein Phosphatase 1, Coiled-Coil-Helix-Coiled-Coil-Helix
Domain-Containing Protein 3 Mitochondrial, Protein Phosphatase 1, Regulatory
Subunit 22. |
Amount : |
10 µg |
Source : Escherichia Coli.
CHCHD3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 250 amino acids (1-227 a.a) and having a molecular mass of 28.5kDa.CHCHD3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Coiled-coil-helix-coiled-coil-helix domain containing 3 (CHCHD3), is a protein-coding gene. CHCHD3 is essential for maintenance of mitochondrial crista integrity and mitochondrial function. In addition, CHCHD3 may perform as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. CHCHD3 may also act as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Lung cancer has been associated with CHCHD3.