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Alternative Name : |
AAG11, DRAL, FHL-2, SLIM-3, SLIM3, Four and a half LIM
domains protein 2, LIM domain protein DRAL, Skeletal muscle LIM-protein 3, FHL2, RNA Binding Motif Protein 18, RNA-Binding Motif Protein 18, RBM18. |
Amount : |
25 µg |
Source : Escherichia Coli.
FHL2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 302 amino acids (1-279 a.a) and having a molecular mass of 34.6kDa. FHL2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Four And A Half LIM Domains 2 (FHL2)
belongs to the four-and-a-half-LIM-only protein family. Family members are
comprised of 2 highly conserved, tandemly arranged, zinc finger domains with 4
highly conserved cysteines binding a zinc atom in each zinc finger. The FHL2
protein is assumed to play a part in the assembly of extracellular membranes.
Furthermore, FHL2 is down-regulated during transformation of normal myoblasts
to rhabdomyosarcoma cells and the FHL2 functions as a link between presenilin-2
and an intracellular signaling pathway.