|
|
| Gene : |
ARG1 |
| Gene ID : |
383 |
| Uniprot ID : |
P05089 |
| Alternative Name : |
ARG1 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
ARG1/1126 |
| Isotype : |
Mouse IgG3, kappa |
| Immunogen Information : |
Recombinant fragment (87 Amino acid residues around aa 1-150) of human ARG1 protein |
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Western Blot (2-4ug/ml); ,Immunohistology (Formalin-fixed) (2-4ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),
