|
|
Gene : |
FUT4 |
Gene ID : |
2526 |
Uniprot ID : |
P22083 |
Alternative Name : |
FUT4, ELFT, FCT3A |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
Leu-M1; same as MMA |
Isotype : |
Mouse IgM, kappa |
Immunogen Information : |
U937 histiocytic cell line |
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)