|
|
| Gene : |
CD3D |
| Gene ID : |
915 |
| Uniprot ID : |
P04234 |
| Alternative Name : |
CD3D, T3D |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
OKT3 |
| Isotype : |
Mouse IgG2a Kappa |
| Immunogen Information : |
Human PBMCs were used as immunogen for the CD3 antibody. |
CD3D is one of the several invariant chains that the variable chains of TCR: Alpha beta or Gamma delta TCR contains, and which support surface TCR expression and transduce the TCR signal. CD3D, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK).
FACS analysis: 0.1 µg/10^6 cells
