Monoclonal Antibody to CD3 (Clone: OKT3)

Product code: 10-4089

Clonality : Monoclonal
Application : FACS
Reactivity : Human

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Gene : CD3D
Gene ID : 915
Uniprot ID : P04234
Alternative Name : CD3D, T3D
Format : Purified
Amount : 100 µg
Clone name : OKT3
Isotype : Mouse IgG2a Kappa
Immunogen Information : Human PBMCs were used as immunogen for the CD3 antibody.

CD3D is one of the several invariant chains that the variable chains of TCR: Alpha beta or Gamma delta TCR contains, and which support surface TCR expression and transduce the TCR signal. CD3D, along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK).

Purification : Protein G Chromatography
Content : 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition : Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

FACS analysis: 0.1 µg/10^6 cells


Monoclonal Antibody to CD3 (Clone: OKT3)

Product code: 10-4089
mg

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