|
|
| Gene : |
SPN |
| Gene ID : |
105369261 |
| Uniprot ID : |
P16150 |
| Alternative Name : |
SPN, CD43 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
DF-T1 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Myeloblastic KG1 cells were used as the immunogen for this antibody. |
This antibody recognizes a 95/115/135kDa (depending upon the extent of glycosylation) surface transmembrane glycoprotein, identified as CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein). CD43 is expressed on all thymocytes and T-lymphocytes. Defects in the CD43 molecule are associated with the development of Wiskott-Aldrich syndrome. CD43 is also found in a range of lymphoid and myeloid tumors. Expression of CD43 may be used to identify B-lymphoblastic lymphoma, since the malignant cells in this condition are often CD43 positive. Since CD43 antibody stains granulocytes and their precursors, this antibody may be used as a marker for myeloid tumors. This antibody is also useful in identification and classification of T-cell malignancies.
"Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml)
