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|
| Gene : |
GYPA |
| Gene ID : |
2993 |
| Uniprot ID : |
P02724 |
| Alternative Name : |
GYPA, GPA |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
GYPA/280 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Recombinant human glycophorin A protein |
Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.
Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
