|
|
| Gene : |
HSPD1 |
| Gene ID : |
3329 |
| Uniprot ID : |
P10809 |
| Alternative Name : |
HSPD1, HSP60 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
GROEL/730 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Recombinant human HSP60 protein |
Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp?s), more appropriately called as stress response proteins (srp?s). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone GROEL730 reacts only with human and is useful in distinguishing human hsp60 from other mammalian and bacterial hsp60.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 1mM EDTA Buffer, pH 8.5-9.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)
