|
|
| Uniprot ID : |
P01701 |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
LAM03 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Purified human lambda light chain |
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
ELISA (Use Ab at 2-4ug/ml for coating) (Order Ab without BSA);
