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|
Gene : |
PRLR |
Gene ID : |
5618 |
Uniprot ID : |
P16471 |
Alternative Name : |
PRLR |
Format : |
Purified |
Amount : |
100 µg |
Clone name : |
SPM213 |
Isotype : |
Mouse IgG1, kappa |
Immunogen Information : |
Semi-purified human prolactin receptor |
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (0.5-1ug/ml); ,Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT),(Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.),