|
|
| Gene : |
SHBG |
| Gene ID : |
6462 |
| Uniprot ID : |
P04278 |
| Alternative Name : |
SHBG |
| Format : |
Purified |
| Amount : |
100 µg |
| Clone name : |
SPM605 |
| Isotype : |
Mouse IgG1, kappa |
| Immunogen Information : |
Recombinant full-length human SHBG protein |
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
