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|
| Gene : |
TP53I3 |
| Gene ID : |
9540 |
| Uniprot ID : |
Q53FA7 |
| Alternative Name : |
TP53I3, PIG3, Quinone Oxidoreductase, tumor protein p53 inducible protein 3. |
| Format : |
Purified |
| Amount : |
20 µg |
| Clone name : |
P1C9AT. |
| Isotype : |
Mouse IgG2a heavy chain and ? light chain. |
| Immunogen Information : |
Anti-human TP53I3 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TP53I3 amino acids 1-332 purified from E. coli. |
TP53I3 participates in the generation of reactive oxygen species (ROS). TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1,2-naphtoquinone over 1,4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro). TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.
TP53I3 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:3,000.
