Polyclonal Antibody to TLR1

Fig-1: Western blot analysis of TLR1. Anti- TLR1 antibody (11-3041) was used at 4 µg/ml on (1) Jurkat, (2) EL4 and (3) Raji lysates.

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Fig-1: Western blot analysis of TLR1. Anti- TLR1 antibody (11-3041) was used at 4 µg/ml on (1) Jurkat, (2) EL4 and (3) Raji lysates.

Product code: 11-3041

Clonality :	Polyclonal
Application :	WB
Reactivity :	Mouse, Human

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Gene :	TLR1
Gene ID :	7096
Uniprot ID :	Q15399
Alternative Name :	TLR1, KIAA0012
Format :	Purified
Amount :	100 µg
Isotype :	Rabbit IgG
Immunogen Information :	A partial length recombinant TLR1 protein (amino acids 300-500) was used as the immunogen for this antibody.

Toll/interleukin-1 receptor-like protein (TLR1) is a member of the Toll-like receptor (TLR) family which has close similarity to Drosophila Toll homologs. Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo. TLR1 is a type I transmembrane receptor that characteristically contains an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLRs generally exist as homodimers but TLR6 forms heterodimers with TLR2 and binds lipopeptide components of gram-positive and gram-negative bacterial cell walls. TLR1 is found to be involved in ocular toxoplasmosis, and leprosy. It is highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.

Purification :	Protein A Chromatography
Content :	25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Western blot analysis: 4-6 µg/ml

1. Kwabena Danso, I., Woo, JH., Hoon Baek, S. et al.
Pulmonary toxicity assessment of polypropylene, polystyrene, and polyethylene microplastic fragments in mice.
Toxicol Res. (2024). https://doi.org/10.1007/s43188-023-00224-x
https://link.springer.com/article/10.1007/s43188-023-00224-x#citeas