Recombinant Human Proline-Rich Nuclear Receptor Coactivator 2

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Product code: 32-4473

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2000 throughout India Order now and get it on next 3-4 Weeks (Major Cities)

Download TDS / Manual MSDS

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20 µg

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Shipping Info:

2000 throughout India Order now and get it on next 3-4 Weeks (Major Cities)

Download TDS / Manual MSDS


Alternative Name :	Proline-rich nuclear receptor coactivator 2, PNRC2.
Amount :	20 µg

Source : Escherichia Coli. PNRC2 Human Recombinant produced in E. coli is a single polypeptide chain containing 162 amino acids (1-139) and having a molecular mass of 18kDa. PNRC2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Proline-Rich Nuclear Receptor Coactivator 2 (PNRC2) takes part in controlling the energy balance between energy storage and energy expenditure. PNRC2 is involved in nonsense-mediated mRNA decay (NMD) by operating as a bridge between the mRNA decapping complex and the NMD machinery. PNRC2 is needed for UPF1/RENT1 localization to the P-body and also plays a role as a nuclear receptor coactivator.

Purification :	Greater than 90% as determined by SDS-PAGE.
Content :	The PNRC2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M UREA and 10% glycerol.
Storage condition :	Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
AA sequence :	MGSSHHHHHH SSGLVPRGSH MGSMGGGERY NIPAPQSRNV SKNQQQLNRQ KTKEQNSQMK IVHKKKERGH GYNSSAAAWQ AMQNGGKNKN FPNNQSWNSS LSGPRLLFKS QANQNYAGAK FSEPPSPSVL PKPPSHWVPV SFNPSDKEIM TFQLKTLLKV QV.