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| Alternative Name : |
Histone deacetylase 8, HD8, HDAC8, HDACL1, CDA07, RPD3. |
| Amount : |
10 µg |
Source : Escherichia Coli.
HDAC8 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 383 amino acids (1-377) and having a molecular mass of 42.6kDa.HDAC8 is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Histone deacetylase 8 (HDAC8) is a member of the class 1 of the histone deacetylase/acuc/apha family. HDAC8 is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Histones play a key role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation modifies chromosome structure and affects transcription factor access to DNA.
